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Desensitization of ET(A) endothelin receptor-mediated negative chronotropic response in right atria–species difference and intracellular mechanisms
1. Desensitization of ET(A) endothelin receptor (ET(A)R) was compared between the rat and guinea-pig with regard to negative chronotropic response (NC) in the right atria (RA). 2. ET-1 (100 nM) produced distinct NC in the presence of BQ788 (300 nM), and positive chronotropic response (PC) in the pre...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571041/ https://ncbi.nlm.nih.gov/pubmed/9831916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702125 |
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