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Effect of DMPPO, a phosphodiesterase type 5 inhibitor, on hypoxic pulmonary hypertension in rats

1. Cyclic guanosine 3′–5′-monophosphate (cyclic GMP) is the second messenger of important physiologically active mediators controlling the pulmonary vascular tone. To potentiate the effects of cyclic GMP on the pulmonary vasculature, we used DMPPO, a new selective PDE-5 inhibitor, and examined its a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Eddahibi, Saadia, Raffestin, Bernadette, Le Monnier de Gouville, Anne-Charlotte, Adnot, Serge
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571014/
https://ncbi.nlm.nih.gov/pubmed/9831902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702124
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