Effect of DMPPO, a phosphodiesterase type 5 inhibitor, on hypoxic pulmonary hypertension in rats

1. Cyclic guanosine 3′–5′-monophosphate (cyclic GMP) is the second messenger of important physiologically active mediators controlling the pulmonary vascular tone. To potentiate the effects of cyclic GMP on the pulmonary vasculature, we used DMPPO, a new selective PDE-5 inhibitor, and examined its a...

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Detaylı Bibliyografya
Asıl Yazarlar: Eddahibi, Saadia, Raffestin, Bernadette, Le Monnier de Gouville, Anne-Charlotte, Adnot, Serge
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1998
Konular:
Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571014/
https://ncbi.nlm.nih.gov/pubmed/9831902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702124
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