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Analysis of the influence of nucleotidases on the apparent activity of exogenous ATP and ADP at P2Y(1) receptors
1. ADP is a potent agonist of rat and human P2Y(1) purinoceptors. ATP is a weak competitive antagonist. This study analyses the situation in which P2Y(1) receptors are exposed to ATP in the presence of exogenous ecto-nucleotidases (apyrases) that have high or low ATPase/ADPase activity ratio. 2. Rat...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1998
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571013/ https://ncbi.nlm.nih.gov/pubmed/9831901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702115 |
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