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Modulation of K(+) currents in Xenopus spinal neurons by p2y receptors: a role for ATP and ADP in motor pattern generation
We have investigated the pharmacological properties and targets of p2y purinoceptors in Xenopus embryo spinal neurons. ATP reversibly inhibited the voltage-gated K(+) currents by 10 ± 3 %. UTP and the analogues α,β-methylene-ATP and 2-methylthio-ATP also inhibited K(+) currents. This agonist profile...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2002
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2290272/ https://ncbi.nlm.nih.gov/pubmed/11986373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.013192 |
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