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Modulation of inhibition of ferrochelatase by N-methylprotoporphyrin
Protoporhyrin IX ferrochelatase catalyses the terminal step of the haem-biosynthetic pathway by inserting ferrous iron into protoporphyrin IX. NMPP (N-methylprotoporphyrin), a transition-state analogue and potent inhibitor of ferrochelatase, is commonly used to induce haem deficiency in mammalian ce...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1570166/ https://ncbi.nlm.nih.gov/pubmed/16792525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060753 |
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