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Modulation of inhibition of ferrochelatase by N-methylprotoporphyrin

Protoporhyrin IX ferrochelatase catalyses the terminal step of the haem-biosynthetic pathway by inserting ferrous iron into protoporphyrin IX. NMPP (N-methylprotoporphyrin), a transition-state analogue and potent inhibitor of ferrochelatase, is commonly used to induce haem deficiency in mammalian ce...

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Detalles Bibliográficos
Main Authors: Shi, Zhen, Ferreira, Gloria C.
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1570166/
https://ncbi.nlm.nih.gov/pubmed/16792525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060753
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