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Novel Role for Checkpoint Rad53 Protein Kinase in the Initiation of Chromosomal DNA Replication in Saccharomyces cerevisiae
A novel role for Rad53 in the initiation of DNA replication that is independent of checkpoint or deoxynucleotide regulation is proposed. Rad53 kinase is part of a signal transduction pathway involved in the DNA damage and replication checkpoints, while Cdc7-Dbf4 kinase (DDK) is important for the ini...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Copyright © 2006 by the Genetics Society of America
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569810/ https://ncbi.nlm.nih.gov/pubmed/16816422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.060236 |
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