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Novel Role for Checkpoint Rad53 Protein Kinase in the Initiation of Chromosomal DNA Replication in Saccharomyces cerevisiae

A novel role for Rad53 in the initiation of DNA replication that is independent of checkpoint or deoxynucleotide regulation is proposed. Rad53 kinase is part of a signal transduction pathway involved in the DNA damage and replication checkpoints, while Cdc7-Dbf4 kinase (DDK) is important for the ini...

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Detalhes bibliográficos
Main Authors: Dohrmann, Paul R., Sclafani, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2006 by the Genetics Society of America 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569810/
https://ncbi.nlm.nih.gov/pubmed/16816422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.060236
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