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Quantitative Trait Linkage Analysis Using Gaussian Copulas

Mapping and identifying variants that influence quantitative traits is an important problem for genetic studies. Traditional QTL mapping relies on a variance-components (VC) approach with the key assumption that the trait values in a family follow a multivariate normal distribution. Violation of thi...

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Autores principales: Li, Mingyao, Boehnke, Michael, Abecasis, Gonçalo R., Song, Peter X.-K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Copyright © 2006 by the Genetics Society of America 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569714/
https://ncbi.nlm.nih.gov/pubmed/16751671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.054650
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