Signatures of Demographic History and Natural Selection in the Human Major Histocompatibility Complex Loci

Many lines of evidence show that several HLA loci have experienced balancing selection. However, distinguishing among demographic and selective explanations for patterns of variation observed with HLA genes remains a challenge. In this study we address this issue using data from a diverse set of hum...

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Autors principals: Meyer, Diogo, Single, Richard M., Mack, Steven J., Erlich, Henry A., Thomson, Glenys
Format: Artigo
Idioma:Inglês
Publicat: Copyright © 2006 by the Genetics Society of America 2006
Matèries:
Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569707/
https://ncbi.nlm.nih.gov/pubmed/16702436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.052837
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