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Signatures of Demographic History and Natural Selection in the Human Major Histocompatibility Complex Loci
Many lines of evidence show that several HLA loci have experienced balancing selection. However, distinguishing among demographic and selective explanations for patterns of variation observed with HLA genes remains a challenge. In this study we address this issue using data from a diverse set of hum...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Copyright © 2006 by the Genetics Society of America
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569707/ https://ncbi.nlm.nih.gov/pubmed/16702436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.052837 |
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