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Pharmacogenetics of drug-metabolizing enzymes: implications for a safer and more effective drug therapy
The majority of phase I- and phase II-dependent drug metabolism is carried out by polymorphic enzymes which can cause abolished, quantitatively or qualitatively decreased or enhanced drug metabolism. Several examples exist where subjects carrying certain alleles do not benefit from drug therapy due...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Royal Society
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569528/ https://ncbi.nlm.nih.gov/pubmed/16096104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2005.1685 |
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