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Pharmacogenetics in drug regulation: promise, potential and pitfalls
Pharmacogenetic factors operate at pharmacokinetic as well as pharmacodynamic levels—the two components of the dose–response curve of a drug. Polymorphisms in drug metabolizing enzymes, transporters and/or pharmacological targets of drugs may profoundly influence the dose–response relationship betwe...
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The Royal Society
2005
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569525/ https://ncbi.nlm.nih.gov/pubmed/16096112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2005.1693 |
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