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Pharmacogenetics in drug regulation: promise, potential and pitfalls

Pharmacogenetic factors operate at pharmacokinetic as well as pharmacodynamic levels—the two components of the dose–response curve of a drug. Polymorphisms in drug metabolizing enzymes, transporters and/or pharmacological targets of drugs may profoundly influence the dose–response relationship betwe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Shah, Rashmi R
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569525/
https://ncbi.nlm.nih.gov/pubmed/16096112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2005.1693
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