The Nck-interacting kinase phosphorylates ERM proteins for formation of lamellipodium by growth factors

The mammalian Ste20-like Nck-interacting kinase (NIK) and its orthologs Misshapen in Drosophila and Mig-15 in Caenorhabditis elegans have a conserved function in regulating cell morphology, although through poorly understood mechanisms. We report two previously unrecognized actions of NIK: regulatio...

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Detalhes bibliográficos
Main Authors: Baumgartner, Martin, Sillman, Amy L., Blackwood, Elizabeth M., Srivastava, Jyoti, Madson, Nikki, Schilling, James W., Wright, Jocelyn H., Barber, Diane L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569174/
https://ncbi.nlm.nih.gov/pubmed/16938849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605950103
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