Wnt/Wingless signaling through β-catenin requires the function of both LRP/Arrow and frizzled classes of receptors
BACKGROUND: Wnt/Wingless (Wg) signals are transduced by seven-transmembrane Frizzleds (Fzs) and the single-transmembrane LDL-receptor-related proteins 5 or 6 (LRP5/6) or Arrow. The aminotermini of LRP and Fz were reported to associate only in the presence of Wnt, implying that Wnt ligands form a tri...
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| Udgivet i: | BMC Cell Biol |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156895/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12729465/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2121-4-4 |
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