Wnt/Wingless signaling through β-catenin requires the function of both LRP/Arrow and frizzled classes of receptors

BACKGROUND: Wnt/Wingless (Wg) signals are transduced by seven-transmembrane Frizzleds (Fzs) and the single-transmembrane LDL-receptor-related proteins 5 or 6 (LRP5/6) or Arrow. The aminotermini of LRP and Fz were reported to associate only in the presence of Wnt, implying that Wnt ligands form a tri...

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Vydáno v:	BMC Cell Biol
Hlavní autoři:	Schweizer, Liang, Varmus, Harold
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2003
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156895/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12729465/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2121-4-4
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