Chemical cleavage reactions of DNA on solid support: application in mutation detection
BACKGROUND: The conventional solution-phase Chemical Cleavage of Mismatch (CCM) method is time-consuming, as the protocol requires purification of DNA after each reaction step. This paper describes a new version of CCM to overcome this problem by immobilizing DNA on silica solid supports. RESULTS: D...
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| Publicat a: | BMC Chem Biol |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12744723/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1472-6769-3-1 |
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