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Chemical cleavage reactions of DNA on solid support: application in mutation detection

BACKGROUND: The conventional solution-phase Chemical Cleavage of Mismatch (CCM) method is time-consuming, as the protocol requires purification of DNA after each reaction step. This paper describes a new version of CCM to overcome this problem by immobilizing DNA on silica solid supports. RESULTS: D...

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Detaylı Bibliyografya
Yayımlandı:BMC Chem Biol
Asıl Yazarlar: Bui, Chinh T, Lambrinakos, Andreana, Babon, Jeffrey J, Cotton, Richard GH
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2003
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156887/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12744723/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1472-6769-3-1
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