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Hemoglobin binding of aromatic amines: molecular dosimetry and quantitative structure-activity relationships for N-oxidation.
Aromatic amines are important intermediates in industrial manufacturing. N-Oxidation to N-hydroxyarylamines is a key step in determining the genotoxic properties of aromatic amines. N-Hydroxyarylamines can form adducts with DNA, with tissue proteins, and with the blood proteins albumin and hemoglobi...
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
1993
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1567031/ https://ncbi.nlm.nih.gov/pubmed/8319626 |
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