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Hemoglobin binding of arylamines and nitroarenes: molecular dosimetry and quantitative structure-activity relationships.

N-Oxidation and nitroreduction to yield N-hydroxyarylamines are metabolic steps that are crucial for the genotoxic properties of aromatic amines and nitroarenes, respectively. N-Hydroxyarylamines can form adducts with DNA, tissue proteins, and the blood proteins albumin and hemoglobin in a dose-depe...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijä: Sabbioni, G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1994
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566868/
https://ncbi.nlm.nih.gov/pubmed/7889861
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