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Molecular dosimetry of 2,4-difluoroaniline in humans and rats by determination of hemoglobin adducts.

Exposure to 2,4-difluoroaniline (DFA) was monitored by GC-MS of DFA adducts bound to hemoglobin (Hb). In two studies, involving 20 and 16 workers potentially exposed to low concentrations of DFA, median concentrations of 10 (range 1-83) and 20 (range 4-322) pmole/g Hb were found, respectively. For b...

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Autors principals: Boogaard, P J, Fokkema, G N, Beulink, G D, Bouskill, J, van Sittert, N J
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566831/
https://ncbi.nlm.nih.gov/pubmed/7889854
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