Use of cloned and expressed human liver UDP-glucuronosyltransferases for analysis of drug glucuronide formation and assessment of drug toxicity.

Five cloned human hepatic UDP-glucuronosyltransferase (UGT) cDNAs were stably expressed in tissue culture cell lines. More than 100 drugs and xenobiotics were used as substrates for glucuronidation catalyzed by the cloned human transferases to determine the chemical structures accepted as substrates...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Burchell, B, Ebner, T, Baird, S, Bin Senafi, S, Clarke, D, Brierley, C, Sutherland, L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1994
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566788/
https://ncbi.nlm.nih.gov/pubmed/7698078
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