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Subunit mutations affect ethanol actions on GABA(A) receptors expressed in Xenopus oocytes

1. Mutations of specific amino acids were introduced in transmembrane domains (TM) of GABA(A) receptor α(2), β(1) and γ(2L) subunits. The effects of these mutations on the action of ethanol were studied using the Xenopus oocyte expression system and two-electrode voltage-clamp recording techniques....

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Detalhes bibliográficos
Main Authors: Ueno, Susumu, Wick, Marilee J, Ye, Qing, Harrison, Neil L, Harris, R Adron
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566035/
https://ncbi.nlm.nih.gov/pubmed/10385236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702563
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