Comparison of the effects of [Phe(1)Ψ(CH(2)-NH)Gly(2)]Nociceptin (1-13)NH(2) in rat brain, rat vas deferens and CHO cells expressing recombinant human nociceptin receptors

1. Nociceptin(NC) is the endogenous ligand for the opioid receptor like-1 receptor (NC-receptor). [Phe(1)ΨC(CH(2)-NH)Gly(2)]Nociceptin(1-13)NH(2) ([F/G]NC(1-13)NH(2)) has been reported to antagonize NC actions in peripheral guinea-pig and mouse tissues. In this study, we investigated the effects of...

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Detalhes bibliográficos
Main Authors: Okawa, Hirobumi, Nicol, Beverley, Bigoni, Raffaella, Hirst, Robert A, Calo', Girolamo, Guerrini, Remo, Rowbotham, David J, Smart, Darren, McKnight, Alexander T, Lambert, David G
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566005/
https://ncbi.nlm.nih.gov/pubmed/10369464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702539
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