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Evidence that [Phe(1) ψ(CH(2)-NH)Gly(2)]nociceptin-(1-13)-NH(2), a peripheral ORL-1 receptor antagonist, acts as an agonist in the rat spinal cord

[Phe(1) ψ(CH(2)-NH)Gly(2)]nociceptin-(1-13)-NH(2), a pseudopeptide analogue of nociceptin is an antagonist in peripheral assays. Here, using in vivo electrophysiological recordings of dorsal horn neurones, [Phe(1) ψ(CH(2)-NH)Gly(2)]nociceptin-(1-13)-NH(2) appears to have agonist activity after spina...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Carpenter, Kate J, Dickenson, Anthony H
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1998
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565681/
https://ncbi.nlm.nih.gov/pubmed/9846631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702188
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