Effects of the soluble guanylyl cyclase activator, YC-1, on vascular tone, cyclic GMP levels and phosphodiesterase activity

1. The vasomotor and cyclic GMP-elevating activity of YC-1, a novel NO-independent activator of soluble guanylyl cyclase (sGC), was studied in isolated rabbit aortic rings and compared to that of the NO donor compounds sodium nitroprusside (SNP) and NOC 18. 2. Similarly to SNP and NOC 18, YC-1 (0.3–...

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Bibliografiske detaljer
Main Authors: Galle, Jan, Zabel, Ulrike, Hübner, Ulrich, Hatzelmann, Armin, Wagner, Birgit, Wanner, Christoph, Schmidt, Harald H H W
Format: Artigo
Sprog:Inglês
Udgivet: 1999
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Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565982/
https://ncbi.nlm.nih.gov/pubmed/10369473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702495
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