Functional comparison of muscarinic partial agonists at muscarinic receptor subtypes hM(1), hM(2), hM(3), hM(4) and hM(5) using microphysiometry

1. This study describes the pharmacological comparison of the muscarinic partial agonists sabcomeline, xanomeline and milameline at human cloned muscarinic receptor subtypes (hM(1–5)). 2. Radioligand binding studies at the hM(1–5) muscarinic receptor subtypes were compared with functional studies us...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wood, Martyn D, Murkitt, Karen L, Ho, Michael, Watson, Jeannette M, Brown, Frank, Hunter, A Jacqueline, Middlemiss, Derek N
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1999
Pynciau:
Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565933/
https://ncbi.nlm.nih.gov/pubmed/10323594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702463
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