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Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages
1. Activation of macrophages with lipopolysaccharide (LPS) and low doses of interferon-γ (IFN-γ) induced apoptotic death through a nitric oxide-dependent pathway. 2. Treatment of cells with the immunosuppressors cyclosporin A (CsA) or FK506 inhibited the activation-dependent apoptosis. 3. These drug...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565893/ https://ncbi.nlm.nih.gov/pubmed/10205001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702422 |
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