Role of iNOS in the vasodilator responses induced by L-arginine in the middle cerebral artery from normotensive and hypertensive rats

1. The substrate of nitric oxide synthase (NOS), L-arginine (L-Arg, 0.01 μM−1 mM), induced endothelium-independent relaxations in segments of middle cerebral arteries (MCAs) from normotensive Wistar-Kyoto (WKY) and hypertensive rats (SHR) precontracted with prostaglandin F(2α) (PGF(2α)). These relax...

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Bibliographic Details
Main Authors: Briones, Ana M, Alonso, María J, Marín, Jesús, Salaices, Mercedes
Format: Artigo
Language:Inglês
Published: 1999
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565787/
https://ncbi.nlm.nih.gov/pubmed/10051127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702281
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