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Extracellular L-arginine is required for optimal NO synthesis by eNOS and iNOS in the rat mesenteric artery wall

1. The formation of NO from endothelial nitric oxide synthase (eNOS) in rat superior mesenteric artery rings was dependent on extracellular L-arginine, and was optimal at a concentration of L-arginine close to the plasma level (carbachol-stimulated NO: control 15.7±0.9, L-arginine 100 μM 22.8±1.3 nM...

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Библиографические подробности
Главные авторы: MacKenzie, Andrew, Wadsworth, Roger M
Формат: Artigo
Язык:Inglês
Опубликовано: 2003
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573978/
https://ncbi.nlm.nih.gov/pubmed/12922936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705380
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