Functional effects of the muscarinic receptor agonist, xanomeline, at 5-HT(1) and 5-HT(2) receptors

1. Xanomeline [3(3-hexyloxy-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine] has been reported to act as a functionally selective muscarinic partial agonist with potential use in the treatment of Alzheimer's disease. This study examined the functional activity of xanomeline at 5-HT(1...

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Autors principals: Watson, J, Brough, S, Coldwell, M C, Gager, T, Ho, M, Hunter, A J, Jerman, J, Middlemiss, D N, Riley, G J, Brown, A M
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565721/
https://ncbi.nlm.nih.gov/pubmed/9884068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702201
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