The mechanism of the nitric oxide-mediated enhancement of tert-butylhydroperoxide-induced DNA single strand breakage

1. Caffeine (Cf) enhances the DNA cleavage induced by tert-butylhydroperoxide (tB-OOH) in U937 cells via a mechanism involving Ca(2+)-dependent mitochondrial formation of DNA-damaging species (Guidarelli et al., 1997b). Nitric oxide (NO) is not involved in this process since U937 cells do not expres...

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Main Authors: Guidarelli, Andrea, Clementi, Emilio, Sciorati, Clara, Cantoni, Orazio
Format: Artigo
Jezik:Inglês
Izdano: 1998
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Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565669/
https://ncbi.nlm.nih.gov/pubmed/9846647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702159
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