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Opposite effects of nitric oxide donors on DNA single strand breakage and cytotoxicity caused by tert-butylhydroperoxide

1. The effects of three different NO donors on tert-butylhydroperoxide (tB-OOH)-induced DNA cleavage and toxicity were investigated in U937 cells. 2. Treatment with S-nitroso-N-acetyl-penicillamine (SNAP, 1–30 μM), while not in itself DNA-damaging, potentiated the DNA strand scission induced by 200 ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Guidarelli, Andrea, Sestili, Piero, Cantoni, Orazio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565287/
https://ncbi.nlm.nih.gov/pubmed/9579724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701683
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