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Enhanced expression of G protein-coupled receptor kinase 2 selectively increases the sensitivity of A(2A) adenosine receptors to agonist-induced desensitization

1. G protein-coupled receptor kinases (GRKs) are thought to be important in mediating the agonist-induced phosphorylation and consequent desensitization of G protein-coupled receptor (GPCR) responses. We have previously shown that stable expression of a dominant negative mutant G protein- coupled re...

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Détails bibliographiques
Auteurs principaux: Mundell, Stuart J, Luty, Jason S, Willets, Jon, Benovic, Jeffrey L, Kelly, Eamonn
Format: Artigo
Langue:Inglês
Publié: 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565629/
https://ncbi.nlm.nih.gov/pubmed/9786508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702081
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