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Inhibition by nitric oxide-releasing compounds of prostacyclin production in human endothelial cells

1. The effects of two chemically unrelated nitric oxide (NO)-releasing compounds were studied on prostacyclin production in lipopolysaccharide (LPS)-stimulated human umbilical vein endothelial cells (HUVECs). The cells expressed cyclooxygenase-2 (COX-2) protein and produced prostacyclin by NS-398-se...

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Autores principales: Kosonen, Outi, Kankaanranta, Hannu, Malo-Ranta, Ulla, Ristimäki, Ari, Moilanen, Eeva
Formato: Artigo
Lenguaje:Inglês
Publicado: 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565612/
https://ncbi.nlm.nih.gov/pubmed/9786495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702042
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