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Down-Regulation of Tristetraprolin Expression Results in Enhanced IL-12 and MIP-2 Production and Reduced MIP-3α Synthesis in Activated Macrophages

In inflammation, the post-transcriptional regulation of transiently expressed genes provides a potential therapeutic target. Tristetraprolin (TTP) is of the factors regulating decay of cytokine mRNAs. The aim of the present study was to identify cytokines whose expression is regulated by TTP. We est...

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Detalhes bibliográficos
Main Authors: Jalonen, Ulla, Nieminen, Riina, Vuolteenaho, Katriina, Kankaanranta, Hannu, Moilanen, Eeva
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1775030/
https://ncbi.nlm.nih.gov/pubmed/17392586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MI/2006/40691
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