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Effect of rolipram and dibutyryl cyclic AMP on resequestration of cytosolic calcium in FMLP-activated human neutrophils

1. We have investigated the effects of the selective phosphodiesterase (PDE) type 4 inhibitor, rolipram (0.01–1 μM) on cytosolic Ca(2+) fluxes in FMLP-activated human neutrophils, as well as on superoxide production by, and release of elastase from, these cells. 2. Cytosolic Ca(2+) fluxes were measu...

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Detalhes bibliográficos
Main Authors: Anderson, R, Mahomed, A Goolam, Theron, A J, Ramafi, G, Feldman, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565405/
https://ncbi.nlm.nih.gov/pubmed/9647480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701849
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