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Accelerated resequestration of cytosolic calcium and suppression of the pro-inflammatory activities of human neutrophils by CGS 21680 in vitro

1. We have investigated the effects of the adenosine A(2A) receptor agonist CGS 21680 (0.01–1 μM) on reactive oxidant production by, and elastase release from FMLP-activated human neutrophils, as well as on cytosolic Ca(2+) fluxes and intracellular concentrations of cyclic AMP. 2. Oxidant production...

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Détails bibliographiques
Auteurs principaux: Anderson, R, Visser, S S, Ramafi, G, Theron, A J
Format: Artigo
Langue:Inglês
Publié: 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572119/
https://ncbi.nlm.nih.gov/pubmed/10864876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703344
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