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Accelerated resequestration of cytosolic calcium and suppression of the pro-inflammatory activities of human neutrophils by CGS 21680 in vitro
1. We have investigated the effects of the adenosine A(2A) receptor agonist CGS 21680 (0.01–1 μM) on reactive oxidant production by, and elastase release from FMLP-activated human neutrophils, as well as on cytosolic Ca(2+) fluxes and intracellular concentrations of cyclic AMP. 2. Oxidant production...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572119/ https://ncbi.nlm.nih.gov/pubmed/10864876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703344 |
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