Discovery of novel melanocortin(4) receptor selective MSH analogues

1. We synthesized a novel series of cyclic melanocyte stimulating hormone (MSH) analogues and tested their binding properties on cells transiently expressing the human melanocortin(1) (MC(1)), MC(3), MC(4) and MC(5) receptors. 2. We discovered that compounds with 26 membered rings of [Cys(4),D-Nal(7...

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Bibliographic Details
Main Authors: Schiöth, Helgi B, Mutulis, Felikss, Muceniece, Ruta, Prusis, Peteris, Wikberg, Jarl E S
Format: Artigo
Language:Inglês
Published: 1998
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565364/
https://ncbi.nlm.nih.gov/pubmed/9630346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701804
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