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Discovery of novel melanocortin(4) receptor selective MSH analogues

1. We synthesized a novel series of cyclic melanocyte stimulating hormone (MSH) analogues and tested their binding properties on cells transiently expressing the human melanocortin(1) (MC(1)), MC(3), MC(4) and MC(5) receptors. 2. We discovered that compounds with 26 membered rings of [Cys(4),D-Nal(7...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Schiöth, Helgi B, Mutulis, Felikss, Muceniece, Ruta, Prusis, Peteris, Wikberg, Jarl E S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1998
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565364/
https://ncbi.nlm.nih.gov/pubmed/9630346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701804
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