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Heterogeneity and underlying mechanism for inotropic action of endothelin-1 in rat ventricular myocytes

1. To clarify the mechanisms underlying the positive inotropic action of endothelin-1 (ET-1), we investigated the effect of ET-1 on twitch cell shortening and the Ca(2+) transient in rat isolated ventricular myocytes loaded with a fluorescent Ca(2+) indicator indo-1. 2. There was a cell-to-cell hete...

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Autores principales: Katoh, Hideki, Terada, Hajime, Iimuro, Masaru, Sugiyama, Shiho, Qing, Ke, Satoh, Hiroshi, Hayashi, Hideharu
Formato: Artigo
Lenguaje:Inglês
Publicado: 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565299/
https://ncbi.nlm.nih.gov/pubmed/9579729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701743
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