SB-205384: a GABA(A) receptor modulator with novel mechanism of action that shows subunit selectivity

1. SB-205384, and its (+) enantiomer (+)-SB-205384 were tested for their modulatory effects on human GABA(A) receptor subunit combinations expressed in Xenopus oocytes by electrophysiological methods. 2. The slowing of the decay rate induced by SB-205384 on native GABA-activated currents in rat neur...

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Main Authors: Meadows, H J, Kumar, C S, Pritchett, D B, Blackburn, T P, Benham, C D
Formato: Artigo
Idioma:Inglês
Publicado: 1998
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Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565273/
https://ncbi.nlm.nih.gov/pubmed/9559912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701721
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