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Receptor mechanisms involved in the 5-HT-induced inotropic action in the rat isolated atrium

1. The effects of 5-hydroxytryptamine (5-HT) in rat cardiac preparations were studied. 5-HT up to 10 μM failed to affect contractility in papillary muscles. However, in electrically driven (1 Hz) left atria 5-HT exerted a positive inotropic effect that started at 1 μM and attained its maximum at 10 ...

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Hlavní autoři: Läer, Stephanie, Remmers, Freerk, Scholz, Hasso, Stein, Birgitt, Ulrich Müller, Frank, Neumann, Joachim
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565259/
https://ncbi.nlm.nih.gov/pubmed/9559903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701702
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