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Receptor mechanisms involved in the 5-HT-induced inotropic action in the rat isolated atrium
1. The effects of 5-hydroxytryptamine (5-HT) in rat cardiac preparations were studied. 5-HT up to 10 μM failed to affect contractility in papillary muscles. However, in electrically driven (1 Hz) left atria 5-HT exerted a positive inotropic effect that started at 1 μM and attained its maximum at 10 ...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565259/ https://ncbi.nlm.nih.gov/pubmed/9559903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701702 |
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