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Role of K(+) channel opening and stimulation of cyclic GMP in the vasorelaxant effects of nicorandil in isolated piglet pulmonary and mesenteric arteries: relative efficacy and interactions between both pathways

1. The effects of the K(+) channel opener levcromakalim, the guanylate cyclase stimulant nitroprusside and the dual drug nicorandil (K(+) channel opener and guanylate cyclase stimulant) were analysed in piglet isolated endothelium-denuded pulmonary (PA) and mesenteric (MA) arteries stimulated by nor...

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Detalhes bibliográficos
Main Authors: Pérez-Vizcaíno, Francisco, Cogolludo, Angel L, Villamor, Eduardo, Tamargo, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565245/
https://ncbi.nlm.nih.gov/pubmed/9535012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701693
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