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Potassium channel activation and relaxation by nicorandil in rat small mesenteric arteries

1. We used whole-cell patch clamp to investigate the currents activated by nicorandil in smooth muscle cells isolated from rat small mesenteric arteries, and studied the relaxant effect of nicorandil using myography. 2. Nicorandil (300 μM) activated currents with near-linear current-voltage relation...

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Detalhes bibliográficos
Main Authors: Davie, C S, Kubo, M, Standen, N B
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565748/
https://ncbi.nlm.nih.gov/pubmed/9886763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702232
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