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Effects of nicorandil as compared to mixtures of sodium nitroprusside and levcromakalim in isolated rat aorta

1. The contribution of the relaxant mechanisms of nicorandil (NIC) were analysed by comparing its effects with those of sodium nitroprusside (SNP), levcromakalim (LEM) and mixtures (1:10, 1:30 and 1:100) of SNP:LEM in isolated endothelium-denuded rat aorta. 2. In rings precontracted with KCl (25 mM)...

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Detalhes bibliográficos
Main Authors: Cogolludo, Angel L, Pérez-Vizcaíno, Francisco, Fajardo, Susan, Ibarra, Manuel, Tamargo, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571231/
https://ncbi.nlm.nih.gov/pubmed/10193784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702375
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