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State-dependent NMDA receptor antagonism by Ro 8-4304, a novel NR2B selective, non-competitive, voltage-independent antagonist

1. Subunit-selective blockade of N-methyl-D-aspartate (NMDA) receptors provides a potentially attractive strategy for neuroprotection in the absence of undesirable side effects. Here, we describe a novel NR2B-selective NMDA antagonist, 4-{3-[4-(4-fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-2-hydroxy...

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Bibliografische gegevens
Hoofdauteurs: Kew, James N C, Trube, Gerhard, Kemp, John A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1998
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565193/
https://ncbi.nlm.nih.gov/pubmed/9504387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701634
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