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A new selective antagonist of the nociceptin receptor

[Phe(1)Ψ(CH(2)-NH)Gly(2)]NC(1-13)NH(2) has been tested in the electrically stimulated guinea pig ileum and mouse vas deferens, two nociceptin sensitive preparations. The new compound showed per se little or no effect in the two tissues, but it displaced to the right the concentration-response curves...

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Main Authors: Guerrini, Remo, Calo, Girolamo, Rizzi, Anna, Bigoni, Raffaella, Bianchi, Clementina, Salvadori, Severo, Regoli, Domenico
Format: Artigo
Jezik:Inglês
Izdano: 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565170/
https://ncbi.nlm.nih.gov/pubmed/9489602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701640
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